| Product name |
Andrographolide |
| Origin |
5508-58-7 |
| Appearance |
white powder |
| Assay |
99% |
| Storage |
Cool and Protect from light |
Product Name:Andrographolide
CAS:5508-58-7
MF:C20H30O5
MW:350.45
EINECS:226-852-5
Mol File:5508-58-7.mol
Melting point:229-232 °C(lit.)
alpha -126 º (c=1.5,HAc)
Boiling point:557.3±50.0 °C(Predicted)
Density d421 1.2317
storage temp. +2C to +8C
pka12.36±0.20(Predicted)
form Off-white solid
optical activity[α]20/D 126°, c = 1.5 in acetic acid
λmax223nm(MeOH)(lit.)
Artemisia series products
| Artemisinin |
CAS 63968-64-9 |
Assay:99% |
| Artesunate |
CAS 88495-63-0 |
Assay:99% |
| Artemether |
CAS 71963-77-4 |
Assay:99% |
| Dihydroartemisinin |
CAS 71939-50-9 |
Assay:99% |
Description
Andrographolide is the bitter principle, a colorless and neutral crystalline substance. It is the major labdane diterpenoid isolated from Andrographis paniculate. It exhibits antiviral, anti-inflammatory, and anticancer activities. The underlying mechanism is the inhibition of the mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) signaling (specifically p38 MAPK/ERK1/2) pathway and downstream transcription factors such as nuclear factor kappa B (NF-κB) and nuclear factor of activated T cells (NFAT). Andrographolide is also confirmed with chemopreventive effects against and the inhibitory effects on cancer cell growth in breast, colon, epidermoid, gastric, liver, leukemia, myeloma, peripheral blood lymphocytes, and prostate cancers.
GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
material. Our company has always adhered to the company philosophy of integrity, professionalism, quality first, and
customer service. With the efforts of all the company's employees, it has established long-term
and stable cooperative relations with many domestic and foreign customers, and won the unanimous trust of domestic
and foreign customers. With good comments, our company have made great progress.
Our company takes pioneering and innovative, high-quality and efficient as the code of conduct, and strives to provide
customers with efficient services,
high-quality products, and reasonable prices. We have established a customer demand-oriented, flexible, diverse and customizable service according to the different needs of different customers. Mode, and ultimately achieve the goal of
win-win.
Our company focuses on the future and the world, and will continue to devote itself to technological progress and the
development of new products in the future, hoping to work hand in hand with new and old friends at home and abroad
to create a better future.
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