Manufacturer Supply High Quality CAS 84057-95-4 Ropivacaine

• CAS No.: 84057-95-4
• Formula: C17h26n2o
• EINECS: 200-001-8
• Type: Synthesis Material Intermediates
• Appearance: White Powder
• Quality: Industrial
• Model NO.: TY-02ALI
• Colour: White
• Package: Foil Bag
• Place: China
• Assay: 99%
• Shelf: 2 Years
• Transport Package: 25kg/Drum 5g, 100g, 500g, 1kg, 10kg, 100kg, 200kg
• Specification: 25kg/drum
• Trademark: tongyon
• Origin: China
• Production Capacity: 5000kg/Month

Product Description

 

Product name	Ropivacaine
CAS	84057-95-4
Appearance	white powder
Assay	99%
Storage	Cool and Protect from light

Ropivacaine
Product Name Ropivacaine

CAS 84057-95-4

MF C17H26N2O

MW 274.4

EINECS 200-001-8

MOL File 84057-95-4.mol

Chemical Properties

Melting point 144-146°
alpha  D25 -82.0° (c = 2 in methanoll)
Boiling point 410.2±45.0 °C(Predicted)
Density  1.044±0.06 g/cm3(Predicted)
pka 8.16(at 25ºC)
InChIKey ZKMNUMMKYBVTFN-HNNXBMFYSA-N
CAS DataBase Reference 84057-95-4(CAS DataBase Reference)


Usage And Synthesis
Description

Ropivacaine is an aminoamide local anaesthetic drug commonly marketed by AstraZeneca under the trade name Naropin. Naropin was launched in 1996 in Australia, Denmark, Finland, the Netherlands and Sweden as a local anesthetic. It can be prepared in a number of ways the most efficient involves a three step sequence beginning with L-pipecolic acid. This compound is the first one in this family to be produced as the pure (S)- enantiomer. The (R)-enantiomer has been shown to have cardiotoxic effects. Thus ropivicaine has less cardiovascular and CNS toxicity than bupivacaine. It is a Na channel blocker that is specific for affecting nerve fibers responsible for transmission of pain (Aδ and C) with no effect on fibers responsible for motor function (Aβ). Clinically, it has distinct advantages over bupivacaine. Its effects are slower in onset, less intense and have a shorter duration. This is a result of extensive metabolism in the liver to the 3-hydroxy isomer by CYPIA2 isoenzyme.
Ropivacaine is an anesthetic (numbing medicine) that blocks the nerve impulses that send pain signals to your brain.

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