Manufacturer Supply High Quality CAS 57260-71-6 Tert-Butyl 1-Piperazinecarboxylate

• CAS No.: 57260-71-6
• Formula: C9h18n2o2
• EINECS: 611-489-0
• Type: Synthesis Material Intermediates
• Appearance: White Powder
• Quality: Industrial
• Model NO.: TY-02AL
• Colour: White
• Package: Foil Bag
• Place: China
• Assay: 99%
• Shelf: 2 Years
• Transport Package: 25kg/Drum 5g, 100g, 500g, 1kg, 10kg, 100kg, 200kg
• Specification: 25kg/drum
• Trademark: tongyon
• Origin: China
• Production Capacity: 5000kg/Month

Product Description

 

Product name	tert-Butyl 1-piperazinecarboxylate
CAS	57260-71-6
Appearance	white powder
Assay	99%
Storage	Cool and Protect from light

tert-Butyl 1-piperazinecarboxylate
Product Name tert-Butyl 1-piperazinecarboxylate

CAS 57260-71-6

MF C9H18N2O2

MW 186.25

EINECS 611-489-0

MOL File 57260-71-6.mol

Chemical Properties

Melting point 43-47 °C(lit.)
Boiling point 98-100
Density  1.030±0.06 g/cm3(Predicted)
Flash point >230 °F
storage temp.  Keep in dark place,Inert atmosphere,2-8°C
pka 8.45±0.10(Predicted)
form  Low Melting Crystalline Mass
color  White to light yellow
Water Solubility  Soluble in ethyl acetatee, methanoll and water.
Sensitive  Air Sensitive
BRN  879985
InChIKey CWXPZXBSDSIRCS-UHFFFAOYSA-N
CAS DataBase Reference 57260-71-6(CAS DataBase Reference)
NIST Chemistry Reference T-butyl 1-piperaziencarboxylate(57260-71-6)




Usage And Synthesis
Uses

N-Boc-piperazine is a compound useful in organic synthesis.

Chemical Properties

Waxy Solid

Uses

1-Boc-piperazine undergoes Buchwald-Hartwig amination with various aryl halides to form corresponding amine derivatives. It can be used to synthesize monosubstituted piperazine intermediates of many bioactive molecules and piperazine containing drug substances, such as trazodone.
Uses

1-Boc-piperazine may be used in:
preparation of series of (m-phenoxy)phenyl substituted piperazine derivatives
termination step during synthesis of α,β-poly(2-oxazoline) lipopolymers via living cationic ring opening polymerization
preparation of monosubstituted piperazines, e.g. in the synthesis of indazole DNA gyrase inhibitors
General Description

1-Boc-piperazine is an N-Boc protected piperazine. Crosscoupling of 1-Boc-piperazine with aryl iodides using CuBr/1,1′-bi-2-naphthol (catalyst) and K3PO4 (base) has been reported. 1-Boc-piperazine undergoes Buchwald-Hartwig coupling reactions with aryl halides. 1-Boc-piperazine can be prepared in 80% yield via solvent-free N-Boc protection catalyzed by iodine.

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