Manufacturer Supply High Quality CAS 6559-91-7 Podophyllotoxin

• CAS No.: 518-28-5
• Formula: C22h22o
• EINECS: 208-250-4
• Type: Synthesis Material Intermediates
• Appearance: White Powder
• Quality: Industrial
• Model NO.: TY-79XQ
• Colour: White
• Package: Foil Bag
• Place: China
• Assay: 99%
• Shelf: 2 Years
• Transport Package: 25kg/Drum 5g, 100g, 500g, 1kg, 10kg, 100kg, 200kg
• Specification: 25kg/drum
• Trademark: tongyon
• Origin: China
• Production Capacity: 5000kg/Month

Product Description

 

Product name	Podophyllotoxin
CAS	518-28-5
Appearance	white powder
Assay	99%
Storage	Cool and Protect from light

Podophyllotoxin
Product Name Podophyllotoxin

CAS 518-28-5

MF C22H22O8

MW414.41

EINECS 208-250-4

MOL File518-28-5.mol

Chemical Properties

Melting point 183-184 °C (lit.)
alpha  -110.7 º (c=1, CHCl3)
Boiling point 453.31°C (rough estimate)
Density  1.2649 (rough estimate)
refractive index  1.4480 (estimate)
storage temp.  2-8°C
pka 13.26±0.40(Predicted)
form  Powder
color  White to off-white
optical activity [α]/D 131±2°, c = 1 in chloroforim
Merck  13,7628
BRN  99163
Stability Very Hygroscopic



Usage And Synthesis
Description

Podophyllotoxin (2,3-butyl-4-aromatic naphthene) is isolated from guijiu  (Podophyllum) . There are two species as the main source of podophyllotoxin, Podophyllum hexandrum Royle and Podophyllum peltatum .
Although podophyllotoxin has significant antitumor and antiviral activities, it showed several toxicity and side effects. Podophyllotoxin derivatives, etoposide (VP-16-213), Etopophos, amino sugar etoposide (NK6l1), and teniposide (VM26), have been developed as anticancer drugs. They are used to treat small cell lung cancer, testicular cancer, acute leukemia, malignant lymphoma, etc. But podophyllotoxin derivatives are not free of toxicity. Besides the narrowing of the anticancer spectrum and low water solubility, these drugs could induce severe myelosuppression, gastrointestinal side effects, etc.
Although the synthetic and biosynthetic pathways of podophyllotoxin have been elucidated, it is still the most effective, economic, and fast way to extract podophyllotoxin from the plant.

GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
material. Our company has always adhered to the company philosophy of integrity, professionalism, quality first, and
customer service. With the efforts of all the company's employees, it has established long-term
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