Manufacturer Supply High Quality CAS 490-46-0 Epicatechin Ec

• CAS No.: 490-46-0
• Formula: C15h14o6
• EINECS: 207-710-1
• Type: Synthesis Material Intermediates
• Appearance: White Powder
• Quality: Industrial
• Model NO.: TY-02ALI
• Colour: White
• Package: Foil Bag
• Place: China
• Assay: 99%
• Shelf: 2 Years
• Transport Package: 25kg/Drum 5g, 100g, 500g, 1kg, 10kg, 100kg, 200kg
• Specification: 25kg/drum
• Trademark: tongyon
• Origin: China
• Production Capacity: 5000kg/Month

Product Description

 

Product name	L-Epicatechin
CAS	490-46-0
Appearance	white powder
Assay	99%
Storage	Cool and Protect from light

L-Epicatechin
Product Name L-Epicatechin

CAS 490-46-0

MF C15H14O6

MW 290.27

EINECS 207-710-1

MOL File 490-46-0.mol   Melting point 240 °C (dec.)(lit.)
alpha  -55~-65(D/20ºC)(c=1,CH3OH)
Boiling point 629.2 °C
Density  1.593±0.06 g/cm3(Predicted)
storage temp.  -20°C
pka 9.54±0.10(Predicted)
form  neat
Water Solubility  Soluble in water or alcohol
Merck  13,1912


Description

Epicatechin is a polyketide synthase-derived polyphenol flavonoid that has been found in T. cacao and has diverse biological activities. It scavenges DPPH (Item No. 14805) radicals in a cell-free assay when used at a concentration of 5 μM. (?)-Epicatechin inhibits COX-1 (IC50 = 3.2 μM). It acts synergistically with epigallocatechin gallate (Item No. 70935) to induce apoptosis in, and reduce the proliferation of, PC-9 lung cancer cells when used at a concentration of 200 μM. (?)-Epicatechin (80 mg/kg) reduces LPS-induced increases in plasma creatinine and urea levels in a rat model of renal inflammation.
Chemical Properties

white to light yellow crystal powde

Uses

Potent antioxidant and antineoplastic agent.

Uses

Catechin is a polyphenolic flavonoid that has been isolated from a variety of natural sources including tea leaves, grape seeds, and the wood and bark of trees such as acacia and mahogany. Catechin is a more potent antioxidant than ascorbate or α-tocopherol in certain in vitro lipid peroxidation assays. (?)-Epicatechin is a 2R,3R stereoisomer of catechin. Like catechin, (?)-epicatechin is a powerful antioxidant. It inhibits cyclooxygenase 1 (IC50 = 3.2 μM). Also, at 100 μM, (?)-epicatechin induces apoptosis in human adenocarcinoma PC-9 cells and stimulates the inhibition of tumor necrosis factor-α release from BALB-c/3T3 cells treated with epigallocatechin gallate.

Uses

An antioxidant and natural product from green tea

GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
material. Our company has always adhered to the company philosophy of integrity, professionalism, quality first, and
customer service. With the efforts of all the company's employees, it has established long-term
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Our company takes pioneering and innovative, high-quality and efficient as the code of conduct, and strives to provide
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