Manufacturer Supply High Quality CAS 21829-25-4 Nifedipine

• CAS No.: 21829-25-4
• Formula: C17h18n2o6
• EINECS: 244-598-3
• Type: Synthesis Material Intermediates
• Appearance: White Powder
• Quality: Industrial
• Model NO.: TY-02ALI
• Colour: White
• Package: Foil Bag
• Place: China
• Assay: 99%
• Shelf: 2 Years
• Transport Package: 25kg/Drum 5g, 100g, 500g, 1kg, 10kg, 100kg, 200kg
• Specification: 25kg/drum
• Trademark: tongyon
• Origin: China
• Production Capacity: 5000kg/Month

Product Description

 

Product name	Nifedipine
CAS	21829-25-4
Appearance	white powder
Assay	99%
Storage	Cool and Protect from light

Nifedipine
Product Name Nifedipine

CAS 21829-25-4

MF C17H18N2O6

MW 346.33

EINECS 244-598-3

MOL File 21829-25-4.mol

Chemical Properties

Melting point 171-175 °C
Boiling point 481.08°C (rough estimate)
Density  1.2109 (rough estimate)
refractive index  1.5486 (estimate)
storage temp.  2-8°C
solubility  DMSO: soluble
pka pKa -0.9/>13(DMF,t undefined) (Uncertain)
form  powder
color  yellow
Water Solubility  <0.1 g/100 mL at 19.5 ºC
Merck  14,6528
InChIKey CYCWGQFQPAYBHG-UHFFFAOYSA-N
CAS DataBase Reference 21829-25-4(CAS DataBase Reference)
NIST Chemistry Reference Nifedipine(21829-25-4)




Usage And Synthesis
Pharmacological effects

Nifedipine is a kind of dihydropyridine calcium antagonists, it can inhibit the Ca2 + uptake of cardiac and vascular smooth muscles, and it can expand the coronary artery , increase coronary blood flow,and improve myocardial ischemic tolerance, at the same time, it can expand peripheral arteries and reduce peripheral vascular resistance,and relieve coronary artery spasm, and increase coronary blood flow, improve myocardial ischemia,in order to decrease the blood pressure. Small doses do not affect blood pressure, when expanding coronary artery ,it is a better anti-angina drug .It is used for the prevention and treatment of angina pectoris,with no adverse effects on respiratory function, its efficacy is best particularly for angina pectoris coronary spasm and obstructive airway disease with angina , its efficacy is superior to β-blockers.It is also applied to all types of high blood pressure, including severe and resistant hypertension. Treatment of refractory congestive heart failure may be taking this long. It is also used for the treatment of primary pulmonary hypertension, diffuse esophageal spasm and bronchial asthma, duodenal ulcers, urinary tract obstruction, exercise-induced asthma, achalasia.



GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
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