| Product name |
Polydatin |
| Origin |
65914-17-2 |
| Appearance |
white powder |
| Assay |
99% |
| Storage |
Cool and Protect from light |
Product Name:Polydatin
CAS:65914-17-2
MF:C20H23O9
MW:407.39
EINECS:
Mol File:65914-17-2.mol
Melting point:223-226 °C(lit.)
alpha -55 º (c=1,acetone)
Boiling point:707.7±60.0 °C(Predicted)
Density 1.521±0.06 g/cm3(Predicted)
form White to off-white solid.
pka9.31±0.10(Predicted)
color White to off-white solid.
Artemisia series products
| Artemisinin |
CAS 63968-64-9 |
Assay:99% |
| Artesunate |
CAS 88495-63-0 |
Assay:99% |
| Artemether |
CAS 71963-77-4 |
Assay:99% |
| Dihydroartemisinin |
CAS 71939-50-9 |
Assay:99% |
Description
Polydatin (PD) is a major chemical component of Polygonum cuspidatum and it could also be found in a variety of other sources. PD is a polyphenol belonging to the chemical family of stilbenoids. Previous studies have shown that PD exhibits many pharmacological activities, including cardioprotective, neuroprotective, and antioxidative activities. With vascular dementia (VaD) rat models, PD markedly attenuated cognitive deficits. Biochemical analysis revealed that PD decreased the production of malondialdehyde (MDA) and significantly increased superoxide dismutase and catalase activities. Additionally, PD effectively alleviated the injuries of cultured neurons induced by oxygen-glucose deprivation. The therapeutic potential of PD for VaD seems related to its antioxidative activity and the direct protection of neurons. Furthermore, PD could also effectively inhibit the polymerization of amyloid-β peptides, which is a major mark in the progression of pathogenesis in Alzheimer's disease (AD). These results suggest that PD is a promising drug candidate or nutraceutical for the treatment of VaD and AD.
UsesPolydatin, a type of polyphenolic phytoalexin, has many physiological and pharmacological effects including anti-inflammatory and anti-oxidative activities. Polydatin is an effective candidate drug for the protection of photo-inflammation. Polydatin exhibits therapeutic potential for vascular dementia, most likely due to its anti-oxidant activity and the direct protection of neurons.
UsesTrans-piceid is a stilbenoid that is trans-resveratrol substituted at position 3 by a beta-D-glucosyl residue. It has a role as a metabolite, a potassium channel modulator, an anti-arrhythmia drug, a hepatoprotective agent, an antioxidant and a nephroprotective agent. It is a stilbenoid, a polyphenol, a beta-D-glucoside and a monosaccharide derivative. It derives from a trans-resveratrol.
GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
material. Our company has always adhered to the company philosophy of integrity, professionalism, quality first, and
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