| Product name |
LIQUIRITIGENIN |
| Origin |
578-86-9 |
| Appearance |
white powder |
| Assay |
99% |
| Storage |
Cool and Protect from light |
Product Name:LIQUIRITIGENIN
CAS:578-86-9
MF:C15H12O4
MW:256.25
EINECS:
Mol File:578-86-9.mol
Melting point:206-208°C
Boiling point:529.5±50.0 °C(Predicted)
Density 1.386±0.06 g/cm3(Predicted)
Flash point:207ºC
pka7.71±0.40(Predicted)
Artemisia series products
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CAS 63968-64-9 |
Assay:99% |
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CAS 88495-63-0 |
Assay:99% |
| Artemether |
CAS 71963-77-4 |
Assay:99% |
| Dihydroartemisinin |
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Assay:99% |
Description
Liquiritigenin is an active estrogenic component in extracts of Glycyrrhizae radix. Glycyrrhizae radix (G. radix, licorice, liquorice) is frequently used for life-enhancing properties, for the treatment of injury or swelling, for detoxification in traditional Oriental medicine, as well as a food supplement in many of the countries in the world. Liquiritigenin is a selective estrogen receptor-β (ERβ) agonist. Liquiritigenin activates multiple ER regulatory elements and native target genes with ERβ but not ERα. The ERβ-selectivity of liquiritigenin is due to the selective recruitment of the coactivator steroid receptor coactivator-2 to target genes.
As the targeting ERβ is associated with anti-inflammatory effects, liquiritigenin exerts anti-inflammatory effects. Liquiritigenin is also reported to antihyperlipidemic, antiallergic and antihepatocellular carcinoma effects.
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