Manufacturer Supply High Quality CAS 124832-27-5 Valacyclovir Hydrochloride Valacyclovir HCl

• CAS No.: 124832-27-5
• Formula: C13h21cln6o4
• EINECS: 641-092-8
• Type: Synthesis Material Intermediates
• Appearance: White Powder
• Quality: Industrial
• Model NO.: TY-79XQ
• Colour: White
• Package: Foil Bag
• Place: China
• Assay: 99%
• Shelf: 2 Years
• Transport Package: 25kg/Drum 5g, 100g, 500g, 1kg, 10kg, 100kg, 200kg
• Specification: 25kg/drum
• Trademark: tongyon
• Origin: China
• Production Capacity: 5000kg/Month

Product Description

 

Product name	Valacyclovir hydrochloride
CAS	124832-27-5
Appearance	white powder
Assay	99%
Storage	Cool and Protect from light

Valacyclovir hydrochloride
Product Name Valacyclovir hydrochloride

CAS 124832-27-5

MF C13H21ClN6O4

MW 360.8

EINECS 641-092-8

MOL File 124832-27-5.mol

Chemical Properties

Melting point 170-172°C
storage temp.  Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility  H2O: >20mg/mL
form  solid
color  white
λmax 253nm(H2O)(lit.)
Merck  14,9899


Usage And Synthesis
Description

Valacyclovir hydrochloride, an orally active L-valyl ester of the potent antiviral agent aciclovir, was launched in 1995 in the United Kingdom for the treatment of herpes simplex virus (HSV) infections of the skin and mucous membranes, including initial and recurrent genital herpes. As a prodrug, valaciclovir has an improved pharmacokinetic profile to aciclovir. It is rapidly absorbed after oral administration and extensively converted to aciclovir via first-pass metabolism to achieve plasma levels of aciclovir comparable to those seen with aciclovir via i.v. route. Valacyclovir is then activated selectively in virus-infected cells by viral thymidine kinase to form aciclovir triphosphate in a stepwise fashion. This active species inhibits viral DNA polymerase via irreversible binding to the active site of the enzyme. Once aciclovir is incorporated into the elongating viral DNA, it terminates replication of the viral DNA strand, an antiviral mechanism unique to aciclovir. Valacyclovir is reportedly in clinical trials for the suppression of cytomegalovirus infection and disease in renal transplant patients.

GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
material. Our company has always adhered to the company philosophy of integrity, professionalism, quality first, and
customer service. With the efforts of all the company's employees, it has established long-term
and stable cooperative relations with many domestic and foreign customers, and won the unanimous trust of domestic
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Our company takes pioneering and innovative, high-quality and efficient as the code of conduct, and strives to provide
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