Manufacturer Supply High Quality CAS 721-50-6 Prilocaine

• CAS No.: 721-50-6
• Formula: C13h20n2o
• EINECS: 211-957-0
• Type: Synthesis Material Intermediates
• Appearance: White Powder
• Quality: Industrial
• Model NO.: TY-02AL
• Colour: White
• Package: Foil Bag
• Place: China
• Assay: 99%
• Shelf: 2 Years
• Transport Package: 25kg/Drum 5g, 100g, 500g, 1kg, 10kg, 100kg, 200kg
• Specification: 25kg/drum
• Trademark: tongyon
• Origin: China
• Production Capacity: 5000kg/Month

Product Description

 

Product name	Prilocaine
CAS	721-50-6
Appearance	white powder
Assay	99%
Storage	Cool and Protect from light

Prilocaine
Product Name Prilocaine

CAS 721-50-6

MF C13H20N2O

MW 220.31

EINECS 211-957-0

MOL File 721-50-6.mol

Chemical Properties

Melting point 37-38°
Boiling point bp0.1 159-162°
Density  1.0117 (rough estimate)
refractive index  nD20 1.5298
storage temp.  2-8°C
solubility  Slightly soluble in water, very soluble in acetonee and in ethanol (96 per cent).
form  neat
pka pKa 7.32 or 7.89 (Uncertain)
Water Solubility  6.169g/L(25 ºC)
InChIKey MVFGUOIZUNYYSO-UHFFFAOYSA-N
CAS DataBase Reference 721-50-6(CAS DataBase Reference)
NIST Chemistry Reference Propanamide, n-(2-methylphenyl)-2-(propylamino)-(721-50-6)


Usage And Synthesis
Local anesthetic drug

Prilocaine belongs to amide local anesthetic drug with its anesthesia intensity and speed being similar as lidocaine but with a longer duration period and weaker effect on vasodilation. It has a lower toxicity than lidocaine. It is clinically for local anesthesia, especially suitable for treating patients who are not allowed to use adrenalinee.
[Pharmacological] its 3% solution has a similar local anesthesia efficacy as the anesthesia drug of 2% lidocaine together with adrenalinee. It has a slow onset time which lasts about 6~7min and the duration time of about 1.5~2h. It has a strong penetration capability through mucous membranes. Adrenalinee has a slightly prolonged duration of action. PPB is 55% and T1/2 of about 1.5h. It is subject to liver metabolism with its metabolites nitroso toluidine being able to oxidize hemoglobin to form methemoglobin. It can be transported to the fetus through the placenta.
[Adverse reactions] once the usage amount exceeds 600mg, methaemoglobinaemia can occur with cyanosis, tachycardia, headache, dizziness and weakness occurring.
[Note] patients of anemia, congenital or acquired methaemoglobinaemia, respiratory failure or heart failure and hypoxic patients should be disabled. It is forbidden for applied to obstetric anesthesia.

GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
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