Supply High Quality Antineoplastic Agents CAS 33419-42-0 Etoposide

• Powder: Yes
• Customized: Non-Customized
• Certification: GMP, ISO 9001, USP, BP
• Suitable for: Elderly, Adult
• State: Solid
• Purity: >99%
• Model NO.: TY-02AL
• CAS No.: 33419-42-0
• Appearance: White Powder
• Einecs: 616-396-9
• Assay: 99%
• Shelf: 2 Years
• Transport Package: 25kg/Drum1g, 50g, 500g, 1kg, 10kg, 100kg, 200kg
• Specification: 25kg/drum
• Trademark: tongyon
• Origin: China
• Production Capacity: 5000kg/Month

Product Description

 

Product name	Etoposide
CAS	33419-42-0
Appearance	white powder
Assay	99%
Storage	Cool and Protect from light

Product Name:Etoposide
CAS:33419-42-0
MF:C29H32O13
MW:588.56
EINECS:251-509-1
Mol File:33419-42-0.mol
Melting point:236-251 °C(lit.)
alpha D20 -110.5° (c = 0.6 in chloroforim)
Boiling point:563.9°C (rough estimate)
Density 1.2966 (rough estimate)
refractive index -110.5 ° (C=0.6, CHCl3)
storage temp. Store at RT
solubility DMSO: 30 mg/mL
pka9.8(at 25ºC)
form powder
color white
Water Solubility Insoluble in water.







Description
An antitumur agent that complexes with topoisomerase II and DNA to enhance double-strand and single strand cleavage of DNA and reversible inhitit religation. Blocks the cell cycle in S-phase and G2-phase of the cell cycle. Induces apoptosis in nor
UsesA DNA topoisomerase II inhibitor. Semi-synthetic derivative of podophyllotoxin, related structurally to Teniposide. Antineoplastic.
Usesanticonvulsant
IndicationsEtoposide (VePesid) is a semisynthetic derivative of podophyllotoxin that is produced in the roots of the American mandrake, or May apple. Unlike podophyllotoxin and vinca alkaloids, etoposide does not bind to microtubules. It forms a complex with the enzyme topoisomerase II, which results in a single-strand breakage of DNA. It is most lethal to cells in the S- and G2-phases of the cell cycle. Drug resistance to etoposide is thought to be caused by decreased cellular drug accumulation.


GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
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