Factory Supply Raw Material API CAS 76963-41-2 Nizatidine

• Powder: Yes
• Customized: Non-Customized
• Certification: GMP, ISO 9001, USP, BP
• Suitable for: Elderly, Adult
• State: Solid
• Purity: >99%
• Model NO.: TY-02AL
• CAS: 76963-41-2
• Appearance: White Powder
• Einecs: 616-396-9
• Assay: 99%
• Shelf: 2 Years
• Transport Package: 25kg/Drum 5g, 100g, 500g, 1kg, 10kg, 100kg, 200kg
• Specification: 25kg/drum
• Trademark: tongyon
• Origin: China
• Production Capacity: 5000kg/Month

Product Description

 

Product name	Nizatidine
CAS	76963-41-2
Appearance	white powder
Assay	99%
Storage	Cool and Protect from light

Product Name:Nizatidine
CAS:76963-41-2
MF:C12H21N5O2S2
MW:331.46
EINECS:627-310-4
Mol File:76963-41-2.mol  
Melting point:130-1320C
Boiling point:478.2±45.0 °C(Predicted)
Density 1.249±0.06 g/cm3(Predicted)
storage temp. -20?C Freezer
solubility Sparingly soluble in water, soluble in methanoll.
pka2.1, 6.8(at 25ºC)
form neat
Water Solubility 21.4g/L(temperature not stated)






Description
Nizatidine is a drug successfully developed for inhibiting the gastric acid secretion. In 1987, it was first approved for entering into the market of the United States with the trade name "aixi". Nizatidine, as a kind of potent H2 receptor antagonist, acts on the gastric acid secretion cells and blocks the formation of stomach acid, leading to the reduction of the gastric acid. It can also inhibit the gastric acid secretion resulting from food and chemical stimuli such as gastrin and acetylcholine. The potency is similar to that of ranitidine and superior to that of cimetidine. Clinical studies have shown that the drug can significantly inhibit gastric acid secretion at night for as long as 10 h. Under normal conditions, the drug does not affect the activity of pepsin in the gastric juice but may affect the secretion amount. It has no female antiandrogen effect. It causes no adverse reactions to the cardiovascular nerve and endocrine system, nor does affect the activity of hepatic cytochrome P450 oxidase. It has good oral absorption with the bioavailability being greater than 90% with PBP accounting for 30% and another 30% binding to the cells. 

GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
material. Our company has always adhered to the company philosophy of integrity, professionalism, quality first, and
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to create a better future.