Supply API CAS 81098-60-4 Cisapride

• Powder: Yes
• Customized: Non-Customized
• Certification: GMP, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Solid
• Purity: >99%
• Model NO.: TY-02AL
• CAS: 81098-60-4
• Assay: 99%
• Shelf: 2 Years
• Transport Package: 25kg/Drum1g, 50g, 500g, 1kg, 10kg, 100kg, 200kg
• Specification: 25kg/drum
• Trademark: tongyon
• Origin: China
• Production Capacity: 5000kg/Month

Product Description

 

Product name	Cisapride
CAS	81098-60-4
Appearance	white powder
Assay	99%
Storage	Cool and Protect from light

Product Name:Cisapride
CAS:81098-60-4
MF:C23H29ClFN3O4
MW:465.95
EINECS:279-689-7
Mol File:81098-60-4.mol  
Melting point:109.8 °C
Boiling point:605.4±55.0 °C(Predicted)
Density 1.29±0.1 g/cm3(Predicted)
storage temp. Store at RT
solubility DMSO: ~30 mg/mL
pka13.01±0.40(Predicted)
form solid
color white
Water Solubility 9.319mg/L(30 ºC)



Description

Cisapride is a gastrointestinal pro-motility drug, and was listed in the UK in 1988. It is a benzamide compound without anti-dopaminergic properties and does not have direct cholinergic properties. Its mechanism of action is different from that of metoclopramide and domperidone. It does not affect dopamine receptors, instead acts through acting with different serotonin receptors on the parietal plexus ending of the posterior wall of gastrointestinal organ, promoting the release of wall muscle acetylcholine (in quantity and time), further stimulating the entire digestive system organs and exerting an pro-motility effect. It does not affect the submucosal plexus, does not change the secretion of mucous membranes, belonging to a driving force drugs. This product can enhance the contraction and peristalsis of the human esophagus, stomach and duodenum, further improving the coordination of gastric antral duodenal region and preventing gastroesophageal and duodenal reflux. It can strengthen the emptying of the stomach and duodenum, and can promote the peristalsis of the large intestine and small intestine. It is mainly used for the treatment of gastrointestinal motility disorders, such as functional dyspepsia, gastroesophageal reflux disease, chronic constipation, bile reflux gastritis, neonatal vomiting and non-ulcer dyspepsia. Second, it can also be used for the treatment of non-gastrointestinal motility disorders, such as diabetic neurogenic bladder, gallbladder contraction disorders.


GuangZhou TongYi biochemistry technology Co.,LTD is a company specializing in active pharmaceutical ingredient (API), biology,plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw material. Our company has always adhered to the company philosophy of integrity, professionalism, quality first, and customer service. With the efforts of all the company's employees, it has established long-term and stable cooperative relations with many domestic and foreign customers, and won the unanimous trust of domestic and foreign customers. With good comments, our company have made great progress.
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