Manufacturer Supply High Quality CAS 90729-43-4 Ebastine

• CAS No.: 90729-43-4
• Formula: C32h39no2
• EINECS: 635-609-6
• Type: Synthesis Material Intermediates
• Appearance: White Powder
• Quality: Industrial
• Model NO.: TY-79XQ
• Colour: White
• Package: Foil Bag
• Place: China
• Assay: 99%
• Shelf: 2 Years
• Transport Package: 25kg/Drum 5g, 100g, 500g, 1kg, 10kg, 100kg, 200kg
• Specification: 25kg/drum
• Trademark: tongyon
• Origin: China
• Production Capacity: 5000kg/Month

Product Description

 

Product name	Ebastine
CAS	90729-43-4
Appearance	white powder
Assay	99%
Storage	Cool and Protect from light

Ebastine
Product Name Ebastine

CAS 90729-43-4

MF C32H39NO2

MW 469.66

EINECS 635-609-6

MOL File 90729-43-4.mol

Chemical Properties

Melting point 80-82°C
Boiling point 596.3±50.0 °C(Predicted)
Density  1.09±0.1 g/cm3(Predicted)
storage temp.  2-8°C
solubility  Slightly soluble in chloroforim, methanoil.
form  solid
pka 8.19±0.10(Predicted)
color  white
Merck  14,3484
CAS DataBase Reference 90729-43-4(CAS DataBase Reference)


Usage And Synthesis
Description

Ebastine belongs to an effective second generation histamine H1 receptor antagonist. One important property of it is that it doesn't penetrate the blood brain barrier. Therefore, it is capable of blocking the H1 receptor in peripheral tissue without having some specific side effects such as sedation and drowsiness. Ebastine is mainly applied for the treatment of allergic rhinitis, pruritus as well as acting as an alternative drug in Decongestant. Upon entering into the human body, it can subject to the action of hepatic cytochrome P450 3A4 to be converted to an active carboxylic acid metabolite, carebastine. The later one is the major active form in vivo. Under certain range, it can inhibit T cell proliferation and the production of Th2-type pro-inflammatory cytokines through macrophages. Ebastine generally has a high safety property without causing cognitive/psychomotor impairment and sedation, like placebo. However, it can cause side effects such as inflammation of the air-cavities around nose, sore throat, indigestion, nausea, headache, and abdominal pain.

GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
material. Our company has always adhered to the company philosophy of integrity, professionalism, quality first, and
customer service. With the efforts of all the company's employees, it has established long-term
and stable cooperative relations with many domestic and foreign customers, and won the unanimous trust of domestic
and foreign customers. With good comments, our company have made great progress.

Our company takes pioneering and innovative, high-quality and efficient as the code of conduct, and strives to provide
customers with efficient services,
high-quality products, and reasonable prices. We have established a customer demand-oriented, flexible, diverse and customizable service according to the different needs of different customers. Mode, and ultimately achieve the goal of
win-win.

Our company focuses on the future and the world, and will continue to devote itself to technological progress and the
development of new products in the future, hoping to work hand in hand with new and old friends at home and abroad
to create a better future.