Manufacturer Supply High Quality CAS 2447-57-6 Sulfadoxine

• CAS No.: 2447-57-6
• Formula: C12h14n4o4s
• EINECS: 219-504-9
• Type: Synthesis Material Intermediates
• Appearance: White Powder
• Quality: Industrial
• Model NO.: TY-02ALI
• Colour: White
• Package: Foil Bag
• Place: China
• Assay: 99%
• Shelf: 2 Years
• Transport Package: 25kg/Drum 5g, 100g, 500g, 1kg, 10kg, 100kg, 200kg
• Specification: 25kg/drum
• Trademark: tongyon
• Origin: China
• Production Capacity: 5000kg/Month

Product Description

 

Product name	Sulfadoxine
CAS	2447-57-6
Appearance	white powder
Assay	99%
Storage	Cool and Protect from light

Product Name:Sulfadoxine
CAS:2447-57-6
MF:C12H14N4O4S
MW:310.33
EINECS:219-504-9
Mol File:2447-57-6.mol    Melting point:190-194°C
Boiling point:298°C (rough estimate)
Density 1.4006 (rough estimate)
refractive index 1.6270 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Soluble in ethanol & ammonium hydroxide (9:1) at 20mg/ml
form powder


The efficacy of sulphadoxine for the treatment of human malaria was first reported in 1964 [1]. Soon thereafter it was found that potentiation took place when sulphadoxine was combined with pyrimethamine for treatment of malaria and monotherapy was abandoned.
Malaria parasites synthesize their folate co-factors and cannot use dietary folic acid as the human host can. Sulphadoxine competes with para-aminobenzoic acid (PABA) for binding to the enzyme dihydropteroate synthetase in the synthesis of dihydropteroate which is an essential substance for the formation of folic acid [2]. It is active against asexual blood forms of P. falciparum but less active against other species. The action is too slow to be used alone for malaria treatment 

GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
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