Manufacturer Supply High Quality CAS 20283-92-5 Rosmarinic Acid

• CAS No.: 20283-92-5
• Formula: C18h16o8
• EINECS: 606-487-1
• Type: Synthesis Material Intermediates
• Appearance: White Powder
• Quality: Industrial
• Model NO.: TY-02ALI
• Colour: White
• Package: Foil Bag
• Place: China
• Assay: 99%
• Shelf: 2 Years
• Transport Package: 25kg/Drum 5g, 100g, 500g, 1kg, 10kg, 100kg, 200kg
• Specification: 25kg/drum
• Trademark: tongyon
• Origin: China
• Production Capacity: 5000kg/Month

Product Description

 

Product name	Rosmarinic acid
CAS	20283-92-5
Appearance	white powder
Assay	99%
Storage	Cool and Protect from light

Product Name Rosmarinic acid

CAS 20283-92-5

MF C18H16O8

MW 360.31

EINECS 606-487-1

MOL File 20283-92-5.mol   Melting point 171-175 °C (lit.)
alpha  +102~+110°(D/20ºC)(c=0.2,C2H5OH)
Boiling point 694.7±55.0 °C(Predicted)
Density  1.33
storage temp.  2-8°C
solubility  H2O: soluble1mg/mL, clear, colorless
form  powder
pka 2.78±0.10(Predicted)
color  white to faintly beige


Usage And Synthesis
Uses

1. Rosmarinic acid is an ester of caffeic acid and 3,4-dihydroxyphenyllactic acid. It is commonly found in species of the Boraginaceae and the subfamily Nepetoideae of the Lamiaceae. However, it is also found in species of other higher plant families and in some fern and hornwort species. Rosmarinic acid has a number of interesting biological activities, e.g. antiviral, antibacterial, antiinflammatory and antioxidant. The presence of rosmarinic acid in medicinal plants, herbs and spices has beneficial and health promoting effects. In plants, rosmarinic acid is supposed to act as a preformed constitutively accumulated defence compound.[sciencedirect]
2. Rosmarinic acid (RA) is one example of a naturally occurring phenolic compound in plants. RA is especially high in Salvia officinalis (garden sage). As an antioxidant, RA possesses both health benefits, and is useful as a food additive to keep foods fresh.Recently, Bakota et al. successfully prepared an extract of Salvia officinalis at three times the levels from sage leaves alone.[thermofisher]
3. Rosmarinic Acid is a phenylpropanoid isolated from Labiatae herbs. The compound exhibits antiinflammatory activity and inhibits the proliferation of murine mesangial cells. Rosmarinic Acid has been shown to dose dependently inhibit migration, adhesion, and invasion of Ls174-T human colon carcinoma cells. Rosmarinic Acid has been documented to increase the melanin content in B16 melanoma cells through activation of protein kinase A. In the same study rosmarinic acid induced the phosphorylation of CRE-binding protein (CREB) and activated cAMP response element (CRE). In the classical complement pathway Rosmarinic Acid inhibited C3-convertase. It also has shown to be an activator of GPR35.[Santaa Cruz]
4. Rosmarinic acid is a naturally-occurring phenolic compound with antioxidant and anti-inflammatory properties. This compound inhibits lipid peroxidation of rat liver microsomes by 90% at a concentration of 25 µg/ml.Rosmarinic acid suppresses endotoxin-induced activation of complement and concomitant formation of prostacyclin.Formation of 5-HETE and LTB from human PMNL is inhibited by rosmarinic acid at concentrations of 10-5 to 10-3 M. [caymanchem]

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