Professional Supply High Purity API CAS 89-25-8 Edaravone

• Powder: Yes
• Customized: Non-Customized
• Certification: GMP, ISO 9001, USP, BP
• Suitable for: Elderly, Adult
• State: Solid
• Purity: >99%
• Model NO.: TY-02AL
• CAS: 89-25-8
• Appearance: White Powder
• Einecs: 616-396-9
• Assay: 99%
• Shelf: 2 Years
• Transport Package: 25kg/Drum 5g, 100g, 500g, 1kg, 10kg, 100kg, 200kg
• Specification: 25kg/drum
• Trademark: tongyon
• Origin: China
• Production Capacity: 5000kg/Month

Product Description

 

Product name	Edaravone
CAS	89-25-8
Appearance	white powder
Assay	99%
Storage	Cool and Protect from light

Product Name:Edaravone
CAS:89-25-8
MF:C10H10N2O
MW:174.2
EINECS:201-891-0
Mol File:89-25-8.mol  
Melting point:126-128 °C(lit.)
Boiling point:287 °C265 mm Hg(lit.)
Density 1,12 g/cm3
refractive index 1.6300 (estimate)
Flash point:191°C/17mm
storage temp. Store at RT
solubility 3.30g/l
pka2.73±0.50(Predicted)
form Crystalline Powder
color Yellow to beige
PH4.0-4.4 (H2O, 20ºC)(saturated aqueous solution)
Water Solubility 3 g/L (20 ºC)  



Edaravone was marketed in Japan for improving neurologic recovery following acute brain infarction. Currently, several agents classified as neuroprotectants and acting by diverse mechanisms (inhibition of glutamate release, blockade of calcium channels, lazaroids) have been marketed for treating the outcomes of brain damage due to trauma, ischemia or cardiac arrest. Edavarone is the first antioxidant with free radical scavenging activity to be introduced for this pathology. This previously described molecule (in particular as norantipyrine, one of three metabolites of antipyrine in mammals) can be simply prepared by direct cyclization of phenylhy  drazine with alkylacetoacetate. Edarevone is a lipophilic agent, readily accessible to brain tissue, that is capable of reducing edema in the brain following ischemia by blocking the arachidonic acid cascade triggering peroxidative neurodegeneration. Interestingly, this agent has been shown to quench active oxygen species in endothelial cell homogenate, as well as inhibiting in vitro lipid peroxidative disintegration of membranes, so making this compound effective during reperfusion following ischemic injury. As an additional indication, phase III trials started with edaravone for increasing the chance of recovery after subarachnoid hemorrhage.
Chemical PropertiesOff white to light yellow powder
Usesantioxidant, lipoxygenase inhibitor
UsesEdaravone inhibits the disease activity in rheumatoid arthritis.



GuangZhou TongYi biochemistry technology Co.,LTD is a company specializing in active pharmaceutical ingredient (API), biology,plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw material. Our company has always adhered to the company philosophy of integrity, professionalism, quality first, and customer service. With the efforts of all the company's employees, it has established long-term and stable cooperative relations with many domestic and foreign customers, and won the unanimous trust of domestic and foreign customers. With good comments, our company have made great progress.
Our company takes pioneering and innovative, high-quality and efficient as the code of conduct, and strives to provide
customers with efficient services,
high-quality products, and reasonable prices. We have established a customer demand-oriented, flexible, diverse and customizable service according to the different needs of different customers. Mode, and ultimately achieve the goal of
win-win.

Our company focuses on the future and the world, and will continue to devote itself to technological progress and the
development of new products in the future, hoping to work hand in hand with new and old friends at home and abroad
to create a better future.