Manufacturer Supply High Quality CAS 95-25-0 Chlorzoxazone

• CAS No.: 95-25-0
• Formula: C7h4clno2
• EINECS: 202-403-9
• Type: Synthesis Material Intermediates
• Appearance: White Powder
• Quality: Industrial
• Model NO.: TY-79XQ
• Colour: White
• Package: Foil Bag
• Place: China
• Assay: 99%
• Shelf: 2 Years
• Transport Package: 25kg/Drum 5g, 100g, 500g, 1kg, 10kg, 100kg, 200kg
• Specification: 25kg/drum
• Trademark: tongyon
• Origin: China
• Production Capacity: 5000kg/Month

Product Description

 

Product name	Chlorzoxazone
CAS	95-25-0
Appearance	white powder
Assay	99%
Storage	Cool and Protect from light

Chlorzoxazone
Product Name Chlorzoxazone

CAS 95-25-0

MF C7H4ClNO2

MW 169.57

EINECS 202-403-9

MOL File 95-25-0.mol

Chemical Properties

Melting point 191-192 °C (lit.)
Density  1.3771 (rough estimate)
refractive index  1.5557 (estimate)
storage temp.  room temp
solubility  DMSO: soluble50mg/mL, clear
form  Powder
pka pKa 8.3 (Uncertain)
color  white to off-white
Water Solubility  0.1 g/100 mL
Merck  14,2194
CAS DataBase Reference 95-25-0(CAS DataBase Reference)
NIST Chemistry Reference Chlorzoxazone(95-25-0)
EPA Substance Registry System Chlorzoxazone (95-25-0)


Usage And Synthesis
Skeletal muscle relaxants

Chlorzoxazone is an orally active central skeletal muscle relaxant with its chemical structure being completely different with all the other muscle relaxants. It, mainly through acting on the central cerebral cortex and the spinal cord, inhibits the multi-synaptic reflection related to muscle spasms and produces muscle relaxation, further relieves the spasm caused pain and increase the flexibility of the muscles involved. Acetaminophen belongs to non-steroidal anti-inflammatory drugs and may mainly exert the analgesic and antipyretic effects through the inhibition of prostaglandin synthesis. Muscle relaxation studies through mouse traction test have demonstrated that the compound Chlorzoxazone showed a dose-dependent muscle relaxant effect with excellent protective effect on the strychnine-induced seizures in mice. The existence of paracetamol in the compound chlorzoxazone tablets can further enhance the effect of chlorzoxazone. Hot plate analgesic tests have showed the compound chlorzoxazone has a significant analgesic effect in a dose-dependent manner. It also has antagonism effect on the painful writhing of mice caused by antimony potassium tartratie in a good dose-response relationship. Test results have showed that acetaminophen and chlorzoxazone analgesic synergy.

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