Grape Seed Extract CAS 84929-27-1 Proanthocyanidin

• Certification: RoHS, ISO, FDA
• Assay Method: HPLC, UV
• Application Form: Tablet, Capsule
• Application: Health Care Products, Medicine
• State: Powder
• Extract Source: Cordate Houttuynia
• Model NO.: TY-02ALI
• Appearance: White Powder
• Einecs: 616-396-9
• Assay: 99%
• Shelf: 2 Years
• Transport Package: 25kg/Drum 1kg, 10kg, 100kg, 200kg
• Specification: 25kg/drum
• Trademark: tongyon
• Origin: China
• Production Capacity: 5000kg/Month

Product Description

 

Product name	Proanthocyanidin
Origin	84929-27-1
Appearance	yellow powder
Assay	99%
Storage	Cool and Protect from light

Product Name:Proanthocyanidin
CAS:84929-27-1
MF:C32H30O11
MW:590.574
EINECS:284-511-6
Mol File:84929-27-1.mol   




Description

Grape seed have good effects on benefit "qi" and blood, strengthen the bones, diuresis, treatment of weak "qi" and blood, lung deficiency and cough, night sweats, palpitations, rheumatism, gonorrhea, and edema, etc. Modern research shows that the original anthocyanin of the grape seed extract has effects on anti-oxidation and reducing cholesterol level, making it a potential natural antioxidant. Therefore, it can be used for prevention and treatment of high cholesterol level, atherosclerosis, cataracts, stomach ulcers, intestinal adenocarcinoma, Ehrlich ascites carcinoma, etc. Its main pharmacological effects are as follows:
1. antioxidant: polyphenols of grape seed extract including proanthocyanidins and the phenolic hydroxyl of gallic acids provide specific hydrogen atoms so that they have a strong antioxidant effect. Its ability of neutralizing and attacking the Iron and oxygen in lipids is 15 to 25 times of the VB. Moreover, it has a stronger effect on scavenging free radical than VC.VE and other antioxidants.
2. anti-radiation effects: inhibit the lipid peroxidation caused by radiation.
3. anti-inflammatory effect: its main component is proanthocyanidins, whose anti-oxidation effect can inhibit the synthesis and release of histamine, serotonin, prostaglandins and leukotrienes and other inflammatory cytokines. It also inhibits the basophils and mast cells to release particles, inhibits the activity of histamine decarboxylase, and limiting the role of hyaluronidase.
4. Prevention of cataracts: Catechins is the main component for cataract prevention; grape seed extract can strengthen the myopic retinal and improve the insight of patients in a non-inflammatory form. It can also relieve the eye fatigue.
5. Anti-cancer effect: It has cytotoxicity to the MCF-7 human breast tumor cells, A-427 human lung cancer cells and human gastric adenocarcinoma cells CRL1739. It also prevents the carcinogenesis effect of intestinal chemical carcinogens.
6. Anti-atherosclerotic effect: Food containing 2.5% grape seed extract, can reduce the cholesterol ester peroxide levels in serum of experimental animal, also lower the LDL (low density lipoprotein) level against atherosclerosis. It can further improve blood rheology and platelet aggregation.
7. Cholesterol-lowering effect: Tannin gallic acid ester can reduce the levels of total plasma cholesterol, triglycerides esters, LDL cholesterol and very low density cholesterol, and increase HDL cholesterol levels.
8. Anti-ulcer effect: The oligomeric proanthocyanidins in grape seed extract can protect the gastric mucosa from damage. Proanthocyanidins can also scavenge the free radical on stomach surface and protect the gastric wall.
9. Anti-mutagenic effect: can reduce the incidence of mitochondria mutation and nuclear mutation.


GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
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